Tissue Engineering: Multiscale Patterning of a Biomimetic Scaffold Integrated with Composite MicrospheresMultiscale Patterning of a Biomimetic Scaffold Integrated with Composite MicrospheresMultiscale Patterning of a Biomimetic Scaffold Integrated with Co
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چکیده
منابع مشابه
Innovative Nano-Composite Biomimetic Scaffold for Osteo-Chondral Tissue Regeneration
Introduction Osteo-chondral articular defects still represent a key concern in modern orthopaedic surgery and several techniques have been so far proposed (1). A novel strategy able to promote cartilage and sub-chondral bone regeneration of full-thickness defects was recently developed, consisting on implantation of a three-layered nano-composite biomimetic scaffold. This peculiar structure mim...
متن کاملHelical Rosette Nanotubes as a Biomimetic Tissue Engineering Scaffold Material
With the rapid development of orthopedic implant technology, various bone implant surgeries and procedures (such as bone fractures, repairing defects, and hip and knee replacements) are routinely performed. Although these surgeries are usually successful operations for up to 15 years, implant failure due to loosening of the prostheses does occur for active or heavy patients. Other patients rece...
متن کاملA Biomimetic Silk Fibroin/Sodium Alginate Composite Scaffold for Soft Tissue Engineering
A cytocompatible porous scaffold mimicking the properties of extracellular matrices (ECMs) has great potential in promoting cellular attachment and proliferation for tissue regeneration. A biomimetic scaffold was prepared using silk fibroin (SF)/sodium alginate (SA) in which regular and uniform pore morphology can be formed through a facile freeze-dried method. The scanning electron microscopy ...
متن کاملHierarchically biomimetic bone scaffold materials: nano-HA/collagen/PLA composite.
A bone scaffold material (nano-HA/ collagen/PLA composite) was developed by biomimetic synthesis. It shows some features of natural bone both in main composition and hierarchical microstructure. Nano-hydroxyapatite and collagen assembled into mineralized fibril. The three-dimensional porous scaffold materials mimic the microstructure of cancellous bone. Cell culture and animal model tests showe...
متن کاملPatterning the surface roughness of a nano fibrous scaffold for transdermal drug release
The main objective of this paper was to manipulate the Nano Fibrous Scaffold "NFS" surface roughness to achieve a new transdermal drug release profile. To assess the intrinsic mechanical properties of Nylon 6 or polycaprolactam, such as its proper resiliency, it was considered as the matrix. Cetirizine was used as a drug model and was loaded (1% w/v) to polymer solution (30%w/v) before spinning...
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ژورنال
عنوان ژورنال: Small
سال: 2014
ISSN: 1613-6810
DOI: 10.1002/smll.201470114